Reddit reviews Foundations of Cellular Neurophysiology (A Bradford Book)
We found 3 Reddit comments about Foundations of Cellular Neurophysiology (A Bradford Book). Here are the top ones, ranked by their Reddit score.
During the rising phase, Na+ influx is maximal whereas K+ efflux is the same as in RMP. This makes it tempting to conclude that Na+ must drive the rising phase. However, It is not K+ efflux, but K+ colliding with the membrane what depolarizes the membrane. the potassium capacitated current does not contribute to the outward potassium current (the one that hyperpolarizes the membrane in which K+ do efflux).
Additionally, the Na/K pump is barely important for the RMP (it accounts for about 6% of the RMP). Ask any frog physiologist that works on nerve preps that are ATP-free for hours and the excitability remains unaltered.
I would suggest also asking expert electrophysiologists:
Joseph LeDoux ([email protected])
Satish Nair ([email protected])
Greg Quirk ([email protected])
The book I linked is priceless for understanding these concepts.
http://www.amazon.com/Foundations-Cellular-Neurophysiology-Bradford-Books/dp/0262100533/ref=sr_1_1?ie=UTF8&qid=1348358421&sr=8-1&keywords=foundations+of+cellular+neurophysiology
Foundation of Cellular Neurophysiology, by Johnston and Wu, provides a in-depth but accessible introduction to the biophysics of action potential propagation, including a full chapter on the role that Nodes of Ranvier play
Axon guide is good but lacks much of the theory behind EPhys.
This book helped me and is worth the money spent: https://www.amazon.com/Foundations-Cellular-Neurophysiology-MIT-Press/dp/0262100533