Reddit reviews Synthesis of Essential Drugs

https://www.amazon.com/Synthesis-Essential-Drugs-Ruben-Vardanyan/dp/0444521666

and a follow on book

https://www.amazon.com/Synthesis-Best-Seller-Drugs-Ruben-Vardanyan/dp/012411492X

The synthesis is not particularly sophisticated. Most of the chemicals are available in even a smaller town drug stores, agricultural supply stores, and hardware stores. You can find patent art on various methods as well, some with more exotic approaches.

This is why synthroid costs pennies per dose to make, and dimes per day to use in many countries.

The folks that are claiming this is a shit-out-of-luck situation are simply wrong. This is practically a high school chem lab exercise to succeed at in a basic way, and the path is there to purify it if required (likely not so important as the mere gross preparation of the chemical).

Most of the critical WHO pharmacopoeia is readily synthesized. These formulations only really cover about 90% of pathologic presentation (aside from mental disorders). The remaining 10% are, to a large degree, a shit-out-of-luck situation for those without resources to pay to ave them made, because they require precursors and resources that are vulnerable to degradation.

Thyroid meds are not, thankfully, in the SOL category.

> https://www.amazon.com/Synthesis-Essential-Drugs-Ruben-Vardanyan/dp/0444521666

Thanks for this one, was already aware of Synthesis of Best Seller Drugs. It's on LibGen, of course.