Reddit reviews Logitech Mouse MX Vertical, 910-005448

Moltissimo, è il secondo che prendo (il precedente era della ANKER ma è durato 3 mesi).
Questo non è esattamente economico, ma li vale. (logitech mx vertical mouse su amazon)

You might want to look up one of those "vertical" mice. I've had more and more problems with the wrist of my mouse hand aching more and more over the years. I got myself one of these Logitech MX Vertical mice a few weeks ago and man, it has done the trick. Pricey, but man, it has helped so much. Aching; Gone.

It took a few weeks to really get used to it, but it's worked incredibly well.
The only real quibbles I have with it are weirdly placed forward/back buttons, the price (which is a tad high) and the fact I keep knocking it all the time when I move my hand over my desk for something without thinking.

Also, obligatory "A controller? Ewww!"
Though in all seriousness, you'd be seriously hamstringing yourself with a controller in STO.

EDIT

Just noting what worked for me. Your mileage may vary.